BETA78

beta78Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plusEndoplasmic reticulum (ER) stress causes beta cell loss and dysfunction in T1D and T2D. Glucose regulated protein 78 (Grp78) is an abundant, widely expressed ER chaperone